Aretha Franklin, best known as the “Queen of Soul,” died Thursday (Aug. 16) following a lengthy battle with advanced pancreatic cancer.

According to TMZ, Franklin passed away around 9:50 a.m. in her Detroit home where she had been under hospice care, her publicist Gwendolyn Quinn told the Associated Press.

The “Respect” singer had been in failing health for several months and was down to 86 pounds, TMZ reported. Sources close to the family say that they were informed over a week ago that Aretha could pass at any time.

Franklin’s family had asked for prayers on Sunday after it was first reported that she was “gravely ill” and near death.

“Franklin’s official cause of death was due to advance pancreatic cancer of the neuroendocrine type, which was confirmed by Franklin’s oncologist, Dr. Philip Phillips of Karmanos Cancer Institute” in Detroit, Quinn told the AP in a statement from Franklin’s family.

“In one of the darkest moments of our lives, we are not able to find the appropriate words to express the pain in our heart. We have lost the matriarch and rock of our family.”

Aretha Franklin was 76 years old and is survived by her four sons and longtime partner Willie Wilkerson.

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She was surrounded by friends and family when she passed. Her family released a statement, saying, “In one of the darkest moments of our lives, we are not able to find the appropriate words to express the pain in our heart. We have lost the matriarch and rock of our family.”

She had appeared incredibly frail in recent years, and rarely performed live. Her most recent appearance was last November for Elton John’s AIDS Foundation 25th Anniversary Benefit.

Aretha’s career is just incredible. Born in Memphis in 1942, her family eventually relocated to Detroit where she began singing in her father’s church. She was such a powerhouse gospel singer, she landed a Columbia record deal in the early ’60s.

Her string of chart-topping hits began with her Atlantic Records deal in 1967.

Aretha’s achievements in the late ’60s were remarkable for any artist, but especially so for a black woman in the midst of the Civil Rights movement. She held the record for the most entries on the Hot 100 list of any female artist for nearly 40 years, only to be dethroned in 2017 by Nicki Minaj.

She won 18 Grammys and was the first woman ever inducted into the Rock ‘n’ Roll Hall of Fame in 1987.

Aretha delivered a powerful rendition of “My Country, ‘Tis of Thee” — while wearing that unforgettable hat — at Barack Obama’s 2009 inauguration.

Throughout her career, Aretha was known for delivering incredible one-off live performances, including at the 2015 Kennedy Center Honors show where she sang ‘Natural Woman’ in honor of the song’s co-writer, Carole King.