Actress Renee Zellweger and a host of other celebrities will be joining forces in L.A. tonight for the second Stand Up to Cancer” telecast.

The live fundraiser will air on many major television networks and will include everything from musical performances to inspirational stories from cancer survivors. The goal of the fundraiser is to build funding for groundbreaking research and get new therapies to cancer patients quickly as possible.

Since its launch in 2008, the “Stand Up to Cancer” campaign has raised more than $100 million for cancer research.